7q11.23

Recent articles

Mother mouse with pups on white

Multiple genes may conspire to lead to autism traits

The many genes implicated in Williams syndrome, a condition related to autism, may all work together to exert their effects on behavior.

By Nicholette Zeliadt
23 December 2019 | 4 min read

Unusual gait marks mice with mutations related to autism

Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.

By Emily Anthes
20 October 2019 | 3 min read
child working on colorful puzzle on lightbox

Duplication of DNA on chromosome 7 increases risk of autism

Roughly one in five children who has an extra piece of chromosome 7 also meets the criteria for an autism diagnosis.

By Jessica Wright
1 February 2018 | 4 min read

Ratio reversal; gender bender; ad accusations and more

The male-dominated sex bias in autism is reversed in a related syndrome, a researcher’s gender could influence her study’s outcome, and an award-nominated ad featuring a young man with autism draws criticism.

By Emily Willingham
12 January 2018 | 4 min read

Tooth fairy delivers drug target for boosting social interest

Cells derived from the dental pulp of children with Williams syndrome hint at a treatment approach for autism.

By Ann Griswold
16 September 2016 | 4 min read

Sequencing studies sharpen focus on key autism genes

Two studies prioritize autism risk genes for further research and illuminate how different types of mutations may work together.

By Jessica Wright
1 October 2015 | 6 min read

Chromosome 7 flaws alter chemical tags throughout genome

Alterations to chromosome 7 lead to changes in the chemical marks that direct gene expression.

By Jessica Wright
21 August 2015 | 3 min read

Behavioral profile of DNA disorder reveals ties to autism

Children who carry an extra copy of part of chromosome 7 have symptoms ranging from social phobia to speech impediments. About one-third of them show signs of autism, according to the first systematic analysis of people with 7q11.23 duplication syndrome.

By Rachel Nuwer
26 May 2015 | 4 min read

Williams syndrome reverses patterns of neuronal branching

The branching patterns of excitatory neurons in people with Williams syndrome are roughly the opposite of the patterns seen normally, according to unpublished results from a small study presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego.

By Jessa Netting
12 November 2013 | 3 min read

Genetics: Williams risk region linked to schizophrenia

The same genetic region that is missing in people with Williams syndrome is likely to be duplicated in some people with schizophrenia, according to a study published 17 July in Biological Psychiatry.

By Jessica Wright
17 September 2013 | 2 min read

Explore more from The Transmitter

Imagining the ultimate systems neuroscience paper

A growing body of papers on systems neuroscience and on giant simulations of neural circuits involves data beyond the point that anyone can reasonably understand end to end. Looking ahead, “paper-bots” could solve that problem.

By Mark Humphries
2 December 2024 | 8 min read
Illustration of a pen hovering over a gene sequence-like series of colored rectangles.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read

What’s next for brain-directed gene therapy after death in Neurogene trial

The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.

By Calli McMurray
26 November 2024 | 6 min read