Akiyoshi Uezu is senior research associate of cell biology and neurobiology at Duke University in Durham, North Carolina.
![](https://www.thetransmitter.org/wp-content/uploads/2017/01/Akiyoshi-Uezu-PictureCC.jpg)
Akiyoshi Uezu
Research associate
Duke University
From this contributor
Exploring the hidden world of inhibitory brain signals
Scientists have discovered more than 100 new proteins at junctions in the brain that dampen neuronal activity.
![](https://www.thetransmitter.org/wp-content/uploads/2017/01/20170124-FarSideSynapes1120.jpg)
Exploring the hidden world of inhibitory brain signals
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Cracking the code of the extracellular matrix
Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.
![Colorful illustration of a latticework of proteins.](https://www.thetransmitter.org/wp-content/uploads/2025/01/ECM-Molofsky-neuroscience-1200-1024x692.png)
Cracking the code of the extracellular matrix
Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.
Huntington’s disease gene variants past a certain size poison select cells
The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.
![A repeated DNA strand extends farther from the left side of the image with each iteration.](https://www.thetransmitter.org/wp-content/uploads/2025/01/1200-hungintons-disease-repeats-cell-death-neuroscience-1024x683.png)
Huntington’s disease gene variants past a certain size poison select cells
The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
![Research image highlighting different brain regions.](https://www.thetransmitter.org/wp-content/uploads/2025/01/1200-transmitter-neuroscience-DDX53-genetic-variants-1024x683.png)
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.