Connectivity
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‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.
Newly found circuit through visual cortex powers first look at faces
The superior colliculus, an evolutionarily ancient brain area responsible for eye movements, responds to faces before the canonical face areas do, a study of macaque monkeys suggests.

Newly found circuit through visual cortex powers first look at faces
The superior colliculus, an evolutionarily ancient brain area responsible for eye movements, responds to faces before the canonical face areas do, a study of macaque monkeys suggests.
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Reporter’s notebook: Highlights from INSAR 2025
The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.

Reporter’s notebook: Highlights from INSAR 2025
The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.
NIDA shutters diversity fellowship program, axes active awards
It’s unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.

NIDA shutters diversity fellowship program, axes active awards
It’s unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.
‘We still exist’: How four neuroscience advocacy groups are navigating federal DEI funding cuts
Trainees from underrepresented backgrounds are losing pillars of support in the current funding climate. Grassroots mentorship organizations are stepping in to continue championing early-career researchers.

‘We still exist’: How four neuroscience advocacy groups are navigating federal DEI funding cuts
Trainees from underrepresented backgrounds are losing pillars of support in the current funding climate. Grassroots mentorship organizations are stepping in to continue championing early-career researchers.