Dementia

Recent articles

Research image of tau proteins in the brains of people with Alzheimer’s disease.

Supersized version of Alzheimer’s protein avoids clumping in brain

“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

By Charles Q. Choi
16 August 2024 | 6 min read
Abstract illustration of antibodies scattered against a peach-colored background.

We found a major flaw in a scientific reagent used in thousands of neuroscience experiments — and we’re trying to fix it.

As part of that ambition, we launched a public-private partnership to systematically evaluate antibodies used to study neurological disease, and we plan to make all the data freely available.

By Mona AlQazzaz, Aled Edwards
5 February 2024 | 6 min read
Composite of images of fruit flies taking flight.

Seen and heard: The Transmitter’s top multimedia stories in 2023

Our audio, video and photo highlights from the past year help to transport readers into scientists’ lives and research, and the lives of their study participants.

By The Transmitter
29 December 2023 | 3 min read

Unmasking Alzheimer’s disease

People with early-onset Alzheimer’s disease describe why they enrolled in clinical trials through the Dominantly Inherited Alzheimer Network (DIAN), in a new book of portrait photography.

By Rebecca Horne
13 November 2023 | 2 min read

Explore more from The Transmitter

Neuroscientists fear Trump’s DEI order may tank diversity-focused grants

Programs that prioritize diversity, equity and inclusion in the field may be at risk, leaving researchers in a “holding pattern,” according to one grant recipient.

By Angie Voyles Askham, Claudia López Lloreda
24 January 2025 | 5 min read
Photograph of Floyd Bloom.

Remembering the life of neuropharmacologist Floyd Bloom

The co-author of the classic textbook “The Biochemical Basis of Neuropharmacology” and pioneer in studying the roles of neurotransmitters in the brain died on 8 January at 88 years old.

By Sydney Wyatt
24 January 2025 | 7 min read
Research image of circuits emerging from striosomes in the striatum.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

By Claudia López Lloreda
24 January 2025 | 4 min read