Defining cell types

Recent articles

This series explores how new high-throughput technologies are changing the way we define brain-cell types—and the challenges that remain.

Get notified every time a new column in this series is published.

-A playful “cellular map” features top-down and bottom-up views of the human brain arranged side-by-side as if they were the earth’s two hemispheres in an old-fashioned map of the world. The brains are colored to suggest land masses and bodies of water.

Knowledge graphs can help make sense of the flood of cell-type data

These tools, widely used in the technology industry, could provide a foundation for the study of brain circuits.

By Michael Hawrylycz
28 May 2024 | 7 min read
Illustration of neurons against a blue background.

Where do cell states end and cell types begin?

High-throughput transcriptomics offers powerful new methods for defining different types of brain cells. But we need to think more explicitly about how we use these data to distinguish a cell’s permanent identity from its transient states.

By Anne E. West
22 April 2024 | 6 min read
An illustration of a gold circle and wavy blue plants.

Building a brain: How does it generate its exquisite diversity of cells?

High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.

By Tomasz Nowakowski, Karthik Shekhar
18 March 2024 | 6 min read
A diagram of many types of cells

Welcome to the second single-cell revolution: New high-throughput technologies are transforming how we define neurons

This ongoing essay series will explore questions these technologies raise, as well as opportunities they provide for understanding development, evolution and disease.

By Joshua R. Sanes
29 January 2024 | 7 min read

Explore more from The Transmitter

By clicking to watch this video, you agree to our privacy policy.
Brain Inspired Microphone

Kim Stachenfeld on the dance between neuroscience and artificial intelligence

As a researcher at both Google DeepMind and Columbia University, Stachenfeld offers cross-disciplinary insight into how to understand the brain.

By Paul Middlebrooks
11 September 2024 | 92 min listen
World map displaying an analysis of years of life lost to suicide among autistic people in 2021.

PPP2R5D gene; social-communication intervention in infants; autism and suicide

Here is a roundup of autism-related news and research spotted around the web for the week of 9 September.

By Jill Adams
10 September 2024 | 2 min read
Illustration with panels depicting two people working together at a computer and a high-five, and a lone researcher in the foreground, looking up.

Should I work with these people? A guide to collaboration

Kevin Bender offers advice for early-career neuroscientists on how to choose the right collaborations and avoid the bad ones.

By Kevin Bender
10 September 2024 | 7 min read