Sequencing
Recent articles
Octopus arm anatomy, molecular makeup revealed in new maps
The datasets provide “a very nice reference” for future functional studies.
Octopus arm anatomy, molecular makeup revealed in new maps
The datasets provide “a very nice reference” for future functional studies.
How long-read sequencing will transform neuroscience
New technology that delivers much more than a simple DNA sequence could have a major impact on brain research, enabling researchers to study transcript diversity, imprinting and more.
How long-read sequencing will transform neuroscience
New technology that delivers much more than a simple DNA sequence could have a major impact on brain research, enabling researchers to study transcript diversity, imprinting and more.
Method pinpoints cell-specific effects of autism-linked mutations
The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.
Method pinpoints cell-specific effects of autism-linked mutations
The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.
Mitochondria mediate effects of PTEN mutations
Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.
Mitochondria mediate effects of PTEN mutations
Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Preprint questions validity of postmortem brain studies
But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.
Preprint questions validity of postmortem brain studies
But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.
Atlas of gene activity in prenatal brain holds clues to autism
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
Atlas of gene activity in prenatal brain holds clues to autism
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
African genetics study NeuroDev shares initial findings
The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.
African genetics study NeuroDev shares initial findings
The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
A mix of common and rare variants shapes autism inheritance patterns
The study also reveals a link between language development and common variants.
A mix of common and rare variants shapes autism inheritance patterns
The study also reveals a link between language development and common variants.
Explore more from The Transmitter
Double-duty neurons in primary olfactory cortex pick up on more than just scent
The cells recognize not only odors, such as bananas and black licorice—but also images and words associated with those smells, according to single-neuron recordings from 17 people.
Double-duty neurons in primary olfactory cortex pick up on more than just scent
The cells recognize not only odors, such as bananas and black licorice—but also images and words associated with those smells, according to single-neuron recordings from 17 people.
How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.
How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.
Former Columbia University psychiatrist committed research misconduct, says federal watchdog
Bret Rutherford, whose research was halted following a suicide in a clinical trial, falsely reported participant eligibility, according to the U.S. Office of Research Integrity.
Former Columbia University psychiatrist committed research misconduct, says federal watchdog
Bret Rutherford, whose research was halted following a suicide in a clinical trial, falsely reported participant eligibility, according to the U.S. Office of Research Integrity.