David Ledbetter is chief clinical officer of Dascena, a personalized medicine company.
David Ledbetter
Chief clinical officer
Dascena
From this contributor
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
There are no autism-specific genes, just brain genes
By
David Ledbetter, Scott Myers
23 March 2021 | 5 min read
Developmental disorders should be viewed as continuum
Intellectual disability, autism, epilepsy and schizophrenia should be considered part of a spectrum of developmental brain dysfunction, says David Ledbetter.
Developmental disorders should be viewed as continuum
By
David Ledbetter
6 May 2013 | 3 min read
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The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.
Exclusive: Janelia sunsets rodent work, launches transparent fish project
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Calli McMurray
22 June 2026 | 5 min read
Transforming AI models into useful model organisms
These systems were not built to explain the brain. But treating them as model organisms that we can perturb and evolve will move us closer to that goal.
Transforming AI models into useful model organisms
These systems were not built to explain the brain. But treating them as model organisms that we can perturb and evolve will move us closer to that goal.
By
Mariya Toneva
22 June 2026 | 6 min read
Cortical area remixes macaques’ knowledge blocks to solve new problems
When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.
Cortical area remixes macaques’ knowledge blocks to solve new problems
When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.
By
Lauren Schenkman
19 June 2026 | 0 min watch