This paper changed my life

Recent articles

Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.

Illustration of a pen hovering over a gene sequence-like series of colored rectangles.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read
Illustration of three columns of text with certain passages underlined and circled.

This paper changed my life: ‘Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,’ from the Fiser Lab

Fiser’s work taught me how to think about grounding computational models in biologically plausible implementations.

By Megan Peters
16 October 2024 | 6 min listen
Illustration of a brain.

This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read
Illustration of three columns of text with a winding path of blank white space where an eraser has been used.

This paper changed my life: ‘Selective erasure of a fear memory’ from the Josselyn Lab

This groundbreaking 2009 paper set a foundation for the types of memories researchers could manipulate and inspired my own approach to science.

By Steve Ramirez
6 August 2024 | 5 min read

Explore more from The Transmitter

Howard Hughes Medical Institute to limit eligible universities for Investigator Program in bid to spread the wealth

The next round of competition, slated for late 2025, will have a new focus, according to an HHMI spokesperson.

By Shaena Montanari
6 December 2024 | 2 min read
Black-and-white photograph of Bryan W Jones holding a camera and pointing it back at the photographer.

An eye for science: Q&A with Bryan W. Jones

The researcher explains how the beauty of the retina drew him into the vision field and why photography reminds him of the value of that work.

By Angie Voyles Askham
6 December 2024 | 7 min read
Human X and Y chromosomes.

Extra Y chromosomes are linked to autism

Data from people with more or fewer than two sex chromosomes could help answer questions around genetic protection and vulnerability.

By Grace Huckins
5 December 2024 | 5 min read