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Illustration by Laurène Boglio
Illustration by Laurène Boglio

Mitochondria and anxiety; brain structure in autism

Researchers reacted to a study of brain mitochondria and behavior in mice and a study of brain structure differences in autism and other conditions. That and more in this week’s Community Newsletter.

Martin Picard of Columbia University detailed his team’s study, “Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice,” published in Nature Communications 10 August. Spectrum published a collection of coverage on the link between mitochondria and autism earlier this week.

Christoph Anacker of Columbia University and D. Parker Kelley of the University of California San Francisco replied to Picard.

Maiko Uemura of Kyoto University and Stefano Berto of the Medical University of South Carolina commented on the study, “Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis,” published in Nature Neuroscience 10 August.

Ashlea Segal of Yale University shared a link to her study, “Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders,” published in Nature Neuroscience 14 August.

Tim Lawn of Kings College London replied to Segal.

The Allen Institute shared the article, “Sharp resolution, big samples: ExA-SPIM microscope accelerates brain imaging,” published in Nature 11 August. Spectrum covered ExA-SPIM on 14 July.


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Steven Sheridan of Harvard University linked to his team’s study, “Loss of function in the neurodevelopmental disease and schizophrenia-associated gene CYFIP1 in human microglia-like cells supports a functional role in synaptic engulfment,” published in Biological Psychiatry 10 August.

Jason Moore of Cedars-Sinai shared a link to the study, “Genome-wide prediction of disease variant effects with a deep protein language model,” published in Nature Genetics 10 August.

Alfred George, Jr. of Northwestern University shared his team’s study, “Epilepsy-associated SCN2A (NaV1.2) variants exhibit diverse and complex functional properties,” published in the Journal of General Physiology 14 August.

Takei Yosuke of the University of Tsukuba posted the article “Unwritten rules of tenure,” published in Spectrum 9 August.

That’s it for this week’s Community Newsletter! If you have any suggestions for interesting social posts you saw in the autism research sphere, feel free to send an email to [email protected].

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