The Early-Stage Investigator Research Grants from the TSC Alliance and the Wong Family Foundation support early-career researchers to drive innovative Tuberous Sclerosis Complex (TSC) research and to foster a diverse group of researchers in this field. Proposals may focus on one of the following:
- Understanding the phenotypic heterogeneity in TSC, i.e., research on genetic/biologic/environmental factors that might explain why TSC is so different from person to person.
- Gaining a deeper knowledge of TSC signaling pathways and the cellular consequences of TSC deficiency.
- Improving TSC disease models, whether cell-based, tissue-based, or animal models.
- Developing clinical biomarkers or patient-reported outcome measures for TSC, particularly those that assess disease burden or stratify an individual’s risk of progression/development of specific manifestations of TSC.
Applicants must be early-career researchers and have a doctoral-level degree, e.g., MD, PhD, or equivalent. The Principal Investigator applicants must be independent researchers, whether tenure-track faculty, non-tenure-track faculty/staff, or at an equivalent level at a research institution or company based in the USA or worldwide. The research grant provides 75,000 USD per year for up to 2 years, including indirect costs.
LOI submission deadline is May 18, 2026. The full application submission deadline is September 8, 2026.