Gene expression
Recent articles
Private initiative makes ‘historic’ investment in autism research
Aligning Research to Impact Autism has committed more than $450 million to build a new multidisciplinary research network to uncover the roots of profound autism and develop treatments.
Private initiative makes ‘historic’ investment in autism research
Aligning Research to Impact Autism has committed more than $450 million to build a new multidisciplinary research network to uncover the roots of profound autism and develop treatments.
Autism-linked variants converge on two molecular patterns in mouse brains
Gene activity across 17 autism mouse models occurs in either of two opposing transcriptomic states, supporting the idea that diverse genetic changes may converge on a few recurring biological patterns.
Autism-linked variants converge on two molecular patterns in mouse brains
Gene activity across 17 autism mouse models occurs in either of two opposing transcriptomic states, supporting the idea that diverse genetic changes may converge on a few recurring biological patterns.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Nuclear location helps control gene activity during brain development
A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.
Nuclear location helps control gene activity during brain development
A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
Cortical territories compete in developmental space race
Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.
Cortical territories compete in developmental space race
Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.
Diverse autism genes derail common developmental pathways
Multiple genetic mouse models initially show delayed cortical development, but the animals’ molecular trajectories diverge within weeks after birth, a new study finds.
Diverse autism genes derail common developmental pathways
Multiple genetic mouse models initially show delayed cortical development, but the animals’ molecular trajectories diverge within weeks after birth, a new study finds.
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Maternity induces lasting gene-expression changes in mouse brains
The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.
Maternity induces lasting gene-expression changes in mouse brains
The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.
Explore more from The Transmitter
Creating community through grant support
Fiona Sanderson, a senior program manager at the Brain Canada Foundation, shares how she got into grant administration and how she helps connect researchers with funding and one another.
Creating community through grant support
Fiona Sanderson, a senior program manager at the Brain Canada Foundation, shares how she got into grant administration and how she helps connect researchers with funding and one another.
This paper changed my life: A first glimpse into the ‘middle’ of brain processing
Work by Jeffrey Moran and Robert Desimone showed that monkeys could focus their attention on different stimuli in their visual field without shifting their gaze. Their work marked a key milestone in the emergence of cognitive neuroscience.
This paper changed my life: A first glimpse into the ‘middle’ of brain processing
Work by Jeffrey Moran and Robert Desimone showed that monkeys could focus their attention on different stimuli in their visual field without shifting their gaze. Their work marked a key milestone in the emergence of cognitive neuroscience.
Acetaminophen effects on developing brain organoids; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 12 October.
Acetaminophen effects on developing brain organoids; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 12 October.