Gene expression
Recent articles
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Maternity induces lasting gene-expression changes in mouse brains
The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.
Maternity induces lasting gene-expression changes in mouse brains
The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.
Brain’s blue spot possesses unexpected structure-function ties
The spatial arrangement of neurons in the locus coeruleus of mice corresponds with the cells’ targets across the brain, according to a new study.
Brain’s blue spot possesses unexpected structure-function ties
The spatial arrangement of neurons in the locus coeruleus of mice corresponds with the cells’ targets across the brain, according to a new study.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
New study questions role of persistent gene activity in memory maintenance
An experiment in sea slugs suggests transcriptional changes might fade after 24 hours.
New study questions role of persistent gene activity in memory maintenance
An experiment in sea slugs suggests transcriptional changes might fade after 24 hours.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.
Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Explore more from The Transmitter
Designer synapses edit brain circuits in living animals
The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.
Designer synapses edit brain circuits in living animals
The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.
Role of GABA-A receptors in dup15q syndrome, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.
Role of GABA-A receptors in dup15q syndrome, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.
Exclusive: Janelia sunsets rodent work, launches transparent fish project
The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.
Exclusive: Janelia sunsets rodent work, launches transparent fish project
The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.