Gut

Research image of enteric neurons in zebrafish.

Opioid receptors may guide formation of gut nervous system in zebrafish

Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.

By Olivia Gieger
26 June 2024 | 4 min read
Three groups of people meet and mix at a crossroads.

Year in Review: Spectrum’s best in 2023

Here are five must-reads from our coverage of autism research over the past 12 months.

28 December 2023 | 4 min read
Digital illustration of Prevotella bacteria.

Gut microbiome meta-analysis reveals consistent autism signal

But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.

By Calli McMurray
22 August 2023 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: COVID-19 conclusions; diagnosis duplication; oxytocin again

This month’s newsletter explores the pandemic’s effects on autism rates, trends in co-occurring mental health conditions, and the impact of intranasal oxytocin.

By Emily Harris
10 November 2022 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Medication timing; oxytocin amounts; sensory sameness

Parents’ health, treatment dosages and sensory perception feature in this month’s crop of null and replicated results.

By Emily Harris
13 October 2022 | 5 min read
Illustration of a pregnant woman in a peach-colored shirt and light red pants standing in profile against a backdrop of chromosomes
Spectrum Microphone

Autism linked to inflammatory bowel disease in parents

The inflammation associated with the disease, particularly in mothers, may contribute to autism traits in children.

By Emily Harris
28 June 2022 | 5 min read

Gut molecule linked to decreased myelination in mouse brains

Targeting the molecule, 4EPS, with an experimental drug may be a way to ease anxiety for autistic people, the researchers say. But not everyone is convinced.

By Angie Voyles Askham
14 February 2022 | 6 min read
Micrograph of intestinal bacteria.

Infection in pregnant mice ups risk of gut problems in pups

Infection during pregnancy can tweak a mouse’s gut microbiome in ways that have lasting effects on her pups’ immune system and increase their chances of gut inflammation, a new study suggests.

By Angie Voyles Askham
18 January 2022 | 5 min read
Illustration: microbes clumped together forming the shape of a brain. The microbes are pink, blue, aqua, and red. Set against a dark blue background.
Spectrum Microphone

Despite flurry of findings, doubts dog gut microbes’ role in autism

The possibility of microbial treatments for autism has inspired a burst of research and nascent clinical trials, but new research suggests these efforts rest on shaky scientific ground.

By Angie Voyles Askham
19 October 2021 | 10 min read
Scanning electron micrograph (SEM) of bacteria cultured from a sample of human faeces.

New library catalogs the human gut microbiome

Researchers put hundreds of gut bacteria strains through their paces to chart the compounds each creates — and to help others explore the flora's potential contribution to autism.

By Rahul Rao
25 August 2021 | 2 min read

Explore more from The Transmitter

Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read