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Neuropixels probe; sex differences in brain anatomy

Researchers on social media reacted to a new version of the Neuropixels probe and a study of sex differences in the brain. That and more in this week’s Community Newsletter.

Nicholas Steinmetz of the University of Washington described his team’s preprint, “Ultra-high density electrodes improve detection, yield, and cell type specificity of brain recordings,” posted on bioRxiv 25 August. Spectrum covered a previous version of the Neuropixels probe last year.

Steinmetz also gave an update on his team’s preprint “Pinpoint: trajectory planning for multi-probe electrophysiology and injections in an interactive web-based 3D environment,” posted on bioRxiv 15 July.

Colin Hoy of the University of California, San Francisco and Guido Meijer of Radboud Universiteit responded to Steinmetz.

Elisa Guma of the U.S. National Institute of Mental Health detailed her team’s preprint, “Comparative neuroimaging of sex differences in human and mouse brain anatomy,” posted on bioRxiv 24 August.

Armin Raznahan, also of the U.S. National Institute of Mental Health, replied to Guma.

Hao Wu of the University of Pennsylvania explained his team’s study, “Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects,” published in Nature Biotechnology 28 August.

Elia Marcos-Grañeda of the National Center for Biotechnology in Spain explained her study, “CUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology,” published in the European Journal of Human Genetics 30 August.

Rogier Kievit of Cambridge University announced his preprint, “No evidence for a link between childhood (6-10y) cellular aging and brain morphology (12y) in a preregistered longitudinal study,” posted on bioRxiv 22 August.

Arielle Keller of the University of Pennsylvania explained her team’s preprint, “A general exposome factor explains individual differences in functional brain network topography and cognition in youth,” posted on bioRxiv 27 August.

Theodore Satterthwaite of the University of Pennsylvania replied to Keller.

Koraima Sotomayor-Enriquez of the University of Edinburgh shared her team’s preprint, “Open dataset of theory of mind reasoning in early to middle childhood,” posted on PsyArXiv 28 August.

Joe Henrich of Harvard University responded to Sotomayor-Enriquez.

That’s it for this week’s Community Newsletter! If you have any suggestions for interesting social posts you saw in the autism research sphere, feel free to send an email to [email protected].

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