Douglas Wallace
Director, Center for Mitochondrial and Epigenomic Medicine
Children's Hospital of Philadelphia
From this contributor
Exploring enigmatic links between mitochondria and autism
Mitochondrial deficits may account for the range of symptoms and neurological deficits seen in autism and explain why it preferentially affects boys, says Douglas Wallace.
Exploring enigmatic links between mitochondria and autism
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Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.