Hindsight is 2020: The year in review

Recent articles

top-down view of the mouse brain

2020 in research images

Feast your eyes on glowing glia and organoids; high-resolution, digital renditions of mouse brains; fluorescent beads passing through zebrafish guts and more.

By Spectrum
23 December 2020 | 1 min read
researcher facing off with the coronavirus.

Rewind: Spectrum’s best from 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

By Spectrum
23 December 2020 | 5 min read
Lab scene during COVID 19 pandemic.

Inside the reporter’s notebook: Dispatches from 2020

Spectrum's staff couldn't report on the ground this year — with no lab visits, sit-down interviews or in-person conferences to attend — but we observed a lot of changes from our computer screens.

By Spectrum
23 December 2020 | 5 min listen
Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Hot topics in autism research, 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

By Spectrum
23 December 2020 | 9 min listen
White lab mouse sitting in a gloved hand.

Notable papers in autism research, 2020

Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

By Spectrum
23 December 2020 | 4 min read

Explore more from The Transmitter

Null and Noteworthy: Neurons tracking sequences don’t fire in order

Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.

By Laura Dattaro
30 June 2025 | 4 min read

How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)

Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.

By Ashley Juavinett
30 June 2025 | 10 min read

Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior

Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.

By Claudia López Lloreda
27 June 2025 | 9 min listen