Prefrontal cortex

Recent articles

Cortical area remixes macaques’ knowledge blocks to solve new problems

When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.

By Lauren Schenkman
19 June 2026 | 0 min watch

Alison Preston explains how our brains form mental frameworks for interpreting the world

Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.

By Paul Middlebrooks
12 March 2025 | 90 min listen
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
Illustration of a neuron with cardinal directions superimposed over it as on a compass.

Neurons’ spikes may convey their whereabouts

The time lag between spurts of activity holds anatomical information, according to a preprint.

By Holly Barker
23 August 2024 | 4 min read
Research image of excitatory synapses in the prefrontal cortex.

Synaptic anomalies in autistic people support imbalance hypothesis

Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.

By Giorgia Guglielmi
27 June 2024 | 4 min read
A brain slice under a microscope.

Preprint questions validity of postmortem brain studies

But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.

By Katie Moisse
5 June 2023 | 6 min read
Brain scans displaying activity in areas linked with social behavior.

People’s perceptions of ‘social’ animations don’t always square with researchers’ labels

The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.

By Charles Q. Choi
22 February 2023 | 6 min read
an image of a neuron

Neurons struggle to spike without fragile X gene

FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.

By Laura Dattaro
17 February 2023 | 3 min read
lllustration of the junction between two nerve cells.

Multi-omics study captures CNTNAP2’s far-ranging effects

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

By Charles Q. Choi
8 December 2022 | 4 min read

Autism-linked mutation disrupts brain circuit to change social behavior

Therapies that target the circuit could boost social activity, new findings suggest.

By Charles Q. Choi
24 June 2022 | 0 min watch

Explore more from The Transmitter

Ilustração de canto de pássaro, cérebro de pássaro e DNA.

Este artigo mudou minha vida: adotando um dos primeiros modelos de neurociência naturalística

Um artigo publicado na PNAS em 1992 mostrou que o canto das aves aumenta a expressão de um gene de resposta imediata no prosencéfalo dessas aves. O estudo revelou a Ribeiro a importância de investigar as respostas moleculares em contextos naturalísticos.

By Sidarta Ribeiro
3 August 2026 | 5 min read
Ilustración del canto de las aves, el cerebro de las aves y el ADN.

Este artículo cambió mi vida: Adoptando un modelo temprano de neurociencia naturalista

Un estudio del 1992 publicado en PNAS demostró que el canto de las aves aumenta la expresión de un gen de respuesta temprana inmediata en el prosencéfalo de los pájaros. El trabajo le reveló a Ribeiro la importancia de estudiar las respuestas moleculares en contextos naturalistas.

By Sidarta Ribeiro
3 August 2026 | 5 min read
Illustration of scientists climbing over a barrier to reach publications.

Scientific talent is global. Access to the world’s scientific stage is not.

Neuroscience in Chile, and across Latin America, does not lack talent or ideas, but the systems that make science visible—prestigious journals, conferences and networks—increasingly price its researchers out.

By Vicente Medel
3 August 2026 | 8 min read