SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

Explore more from The Transmitter

Neurons in cerebral organoids containing a MECP2 variant (right panel) have smaller cell bodies and fewer branches than those in wildtype organoids (left panel).

Autism in Kenya, organoid research, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 22 December.

By Jill Adams
23 December 2025 | 2 min read
Research image of the human dorsal root ganglion.

‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons

The atlas also offers up molecular and cellular targets for new pain therapies.

By Calli McMurray
23 December 2025 | 5 min read
Illustration of a simple circuit.

Not playing around: Why neuroscience needs toy models

Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.

By Marcus Ghosh
22 December 2025 | 6 min read

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