SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

Explore more from The Transmitter

Progenitors cells in the medial ganglionic eminence become increasingly organized during development as rows of brain imaging progress from top to bottom.

‘Tour de force’ study flags fount of interneurons in human brain

The newly discovered cell type might point to the origins of the inhibitory imbalance linked to autism and other conditions.

By Holly Barker
29 January 2026 | 4 min read

Michael Shadlen explains how theory of mind ushers nonconscious thoughts into consciousness

All of our thoughts, mostly nonconscious, are interrogations of the world, Shadlen says. The opportunity to report our answers to ourselves or others brings a thought into conscious awareness.

By Paul Middlebrooks
28 January 2026 | 1 min read
Walter Koroshetz.

‘Peer review is our strength’: Q&A with Walter Koroshetz, former NINDS director

In his first week off the job, the former National Institute of Neurological Disorders and Stroke director urges U.S. scientists to remain optimistic about the future of neuroscience research, even if the executive branch “may not value what we do.”

By Angie Voyles Askham
27 January 2026 | 7 min read

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