SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

Explore more from The Transmitter

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice, but methodological challenges prompt questions about the new evidence.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of myelinated axons.

Oligodendrocytes need mechanical cues to myelinate axons correctly

Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.

By Calli McMurray
11 February 2026 | 5 min read

Modern AI is simply no match for the complexity likely required for harboring consciousness, says Jaan Aru

He argues that our brain’s computations are of a completely different nature than any artificial intelligence because they take place across many spatial and temporal scales and are inextricably entwined with biological materials.

By Paul Middlebrooks
11 February 2026 | 1 min read

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