SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

Explore more from The Transmitter

Genetic profiles separate early, late autism diagnoses

Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.

By Natalia Mesa
27 November 2025 | 5 min read

To persist, memories surf molecular waves from thalamus to cortex

During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.

By Claudia López Lloreda
26 November 2025 | 4 min read

Sex hormone boosts female rats’ sensitivity to unexpected rewards

During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.

By Angie Voyles Askham
26 November 2025 | 5 min read

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