SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

Explore more from The Transmitter

Gene replacement therapy normalizes some traits in SYNGAP1 model mice

The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.

By Charles Q. Choi
20 November 2025 | 5 min read

Does AI understand what it produces? Henk de Regt explores how we might assess understanding in machines and humans

Building on his philosophy of how scientists understand what they work on, de Regt is extending his approach to test understanding in machines.

By Paul Middlebrooks
19 November 2025 | 1 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Role of maternal factors in autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 17 November.

By Jill Adams
18 November 2025 | 2 min read

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