Systems neuroscience

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Different colored rectangles form the shapes of a bird, fish and insect.

Systems and circuit neuroscience need an evolutionary perspective

To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

By Karl Farrow, Katja Reinhard
16 July 2025 | 7 min listen
Illustration of complex, intersecting biological structures.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease

To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

By Michael A. Yassa
16 June 2025 | 7 min read

Escaping groupthink: What animals’ behavioral quirks reveal about the brain

Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

By Angie Voyles Askham
23 May 2025 | 10 min listen
Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Conceptual illustration of four heads studying representations of neural mechanisms.

This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

By Marino Pagan
13 May 2025 | 7 min listen

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Illustration of the outlines of a baby, a bee and a robot filled in with computer code-like characters.

Babies, bees and bots: On the hunt for markers of consciousness

To truly understand consciousness, we need new methods to measure it and detect it in other intelligent systems.

By Tim Bayne
30 July 2025 | 6 min read

Jennifer Prendki explains why AI needs to emulate life

Prendki describes how her work on large artificial-intelligence models shaped her view that current AI needs inspiration from living organisms.

By Paul Middlebrooks
30 July 2025 | 109 min listen
Research visualization of reverberating activity in a selection of higher-order brain areas.

Eye puffs prompt separable sensory, affective brain responses in mice, people

Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.

By Calli McMurray
29 July 2025 | 8 min listen