Alzheimer’s disease
Recent articles
Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.
Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.
‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.
Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.
Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.
Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.
Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.
Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.
Explore more from The Transmitter
Why the 21st-century neuroscientist needs to be neuroethically engaged
Technological advances in decoding brain activity and in growing human brain cells raise new ethical issues. Here is a framework to help researchers navigate them.
Why the 21st-century neuroscientist needs to be neuroethically engaged
Technological advances in decoding brain activity and in growing human brain cells raise new ethical issues. Here is a framework to help researchers navigate them.
Exclusive: Recruitment issues jeopardize ambitious plan for human brain atlas
A lack of six new brain donors may stop the project from meeting its goal to pair molecular and cellular data with the functional organization of the cortex.
Exclusive: Recruitment issues jeopardize ambitious plan for human brain atlas
A lack of six new brain donors may stop the project from meeting its goal to pair molecular and cellular data with the functional organization of the cortex.
How pragmatism and passion drive Fred Volkmar—even after retirement
Whether looking back at his career highlights or forward to his latest projects, the psychiatrist is committed to supporting autistic people at every age.
How pragmatism and passion drive Fred Volkmar—even after retirement
Whether looking back at his career highlights or forward to his latest projects, the psychiatrist is committed to supporting autistic people at every age.