Bioinformatics
Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.
I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.
Gut microbiome meta-analysis reveals consistent autism signal
But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.
Gut microbiome meta-analysis reveals consistent autism signal
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Chromatin remodeling tied to altered splicing in autism model
Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole
‘Dosage sensitivity map’ predicts active ingredients in copy number variants
The catalog of rare copy number variants tied to autism and other conditions could help researchers identify which genes account for the mutations’ effects.
‘Dosage sensitivity map’ predicts active ingredients in copy number variants
Lumping versus splitting with autism-linked variants: A conversation with Vanessa Vogel-Farley and Yssa DeWoody
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Lumping versus splitting with autism-linked variants: A conversation with Vanessa Vogel-Farley and Yssa DeWoody
Meet the company trying precision medicine for autism
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Meet the company trying precision medicine for autism
Alternate RNA versions of genes may shape autism
Autism may involve different levels of RNA isoforms encoded by genes in the brain, which express many more proteins than previously thought.
Alternate RNA versions of genes may shape autism
Protein atlas doubles number of known interactions in mice
Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.
Protein atlas doubles number of known interactions in mice
Ultra-rare variants point to new autism candidate genes
A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.
Ultra-rare variants point to new autism candidate genes
Explore more from The Transmitter
Some minimally verbal autistic people show signs of written-language familiarity, study suggests
But researchers not involved in the work worry the findings could be used to support discredited facilitated-communication techniques.
Some minimally verbal autistic people show signs of written-language familiarity, study suggests
But researchers not involved in the work worry the findings could be used to support discredited facilitated-communication techniques.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
X chromosome inactivation; motor difficulties in 16p11.2 duplication and deletion; oligodendroglia
Here is a roundup of autism-related news and research spotted around the web for the week of 6 May.
X chromosome inactivation; motor difficulties in 16p11.2 duplication and deletion; oligodendroglia
Here is a roundup of autism-related news and research spotted around the web for the week of 6 May.