Bipolar disorder

New resource maps gene expression, regulation in neuron subtypes

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.

By Chloe Williams
1 July 2022 | 4 min read
Young woman sitting alone at window in the shadows.

Autistic LGBTQ+ people report frequent mental health problems

The co-occurring conditions may stem from the heightened stress people in minority communities experience.

By Niko McCarty
16 May 2022 | 2 min read
Book cover conceptual illustration of chromosome superimposed with genetic tree.
Spectrum Microphone

A whisper of autism: Fragile X carriers and the autism phenotype

Among people who carry the fragile X premutation, about 14 percent of boys and 5 percent of girls meet the criteria for autism, but the ‘broad autism phenotype’ may be far more common.

By Anne Skomorowsky
21 April 2022 | 14 min read
Overhead view of crowd of people walking in Copenhagen city square.
Spectrum Microphone

Population study downgrades some copy number variants’ impact on autism

Some copy number variants may boost a person’s chances of having autism, but to a lesser extent than previously thought.

By Charles Q. Choi
28 January 2022 | 5 min read
Pregnant woman holding two white pills in her hand.
Spectrum Microphone

Prenatal exposure to antipsychotic medication does not increase odds of autism, ADHD

Children born to mothers who take antipsychotic drugs during pregnancy are not more likely to have autism or attention deficit hyperactivity disorder, or to be born preterm or underweight.

By Peter Hess
20 August 2021 | 2 min read
Teen girl up at night, looking at her computer.
Spectrum Microphone

Childhood autism traits linked to hypomania in adolescence

Children with autism traits tend to show agitation, excitability, decreased sleep and other mild signs of mania in adolescence; the association is higher in identical twins than fraternal twins, suggesting that genetics plays a role.

By Laura Dattaro
10 May 2021 | 4 min read
Brain hemispheres color-coded.
Spectrum Microphone

Autism shares brain structure changes with other psychiatric conditions

Atypical development of a particular type of neuron explains the structural similarities seen in the brains of people with autism, schizophrenia and other conditions, according to a new study.

By Angie Voyles Askham
1 October 2020 | 5 min read
Variants linked to multiple conditions, including autism, tend to appear in genes that influence brain development, as shown in this chart in blue and grey.

Autism may share inherited variants with other psychiatric conditions

Some of the inherited variants implicated in autism also increase the odds of schizophrenia, bipolar disorder, depression or attention deficit hyperactivity disorder.

By Nicholette Zeliadt
13 January 2020 | 4 min read
A young teen woman sits on stairs with her head hanging down, her face hidden by her hair.

Adolescent anxiety predicts later psychiatric diagnoses in autistic people

People with autism are at increased odds of having other psychiatric conditions, such as anxiety and depression, but the links can be counterintuitive.

By Michael Marshall
2 January 2020 | 4 min read

Model program could divert some 911 calls from police to mental health professionals

Denver, Colorado, is one of at least eight cities considering an Oregon program to decriminalize and improve the treatment of people with severe mental illness -- while saving the city money.

By LJ DAWSON, Kaiser Health News
15 October 2019 | 8 min read

Explore more from The Transmitter

Portrait of Kaspar Podgorski standing in his lab wearing a helmet with a climbing rope over his shoulder.

Climbing to new heights: Q&A with Kaspar Podgorski

The optical physiologist tracks neural computations inside the lab and scales sheer rock faces outside—even after a life-changing fall.

By Elissa Welle
21 June 2024 | 8 min read
Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read

Widely used calcium imaging protocol can lead to spurious results, new paper cautions

The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.

By Angie Voyles Askham
19 June 2024 | 0 min watch