Kevin Bender is professor of neurology at the University of California, San Francisco. His lab focuses on understanding how the brain encodes information at the synaptic, cellular and network level. Work primarily revolves around understanding how ion channels and modulation of ion channels contribute to these processes in health and in neurodevelopmental and neuropsychiatric conditions. This includes studies related to neurodevelopmental channelopathies, for which he is grateful to be able to work with close colleagues and partners from academia, industry and patient advocacy groups.
Kevin Bender
Professor of neurology
University of California, San Francisco
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Selected articles
- “Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD” | Neuron
- “Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites” | Neuron
- “Arrestin-3 Agonism at Dopamine D3 Receptors Defines a Subclass of Second-Generation Antipsychotics That Promotes Drug Tolerance” | Biological Psychiatry
- “The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex” | Neuron
- “Periadolescent Maturation of GABAergic Hyperpolarization at the Axon Initial Segment” | Cell Reports
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Head direction cells stably orient mice to outside world
The cells’ representations show little drift over time—unlike those of other navigation system neurons—and may provide a “rigid backbone” for more flexible sensory and cognitive responses.
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Juan Gallego discusses how manifolds are transforming our understanding of the coordination of neuronal population activity
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