Mark Zylka
Associate Professor
University of North Carolina at Chapel Hill
From this contributor
Few autism researchers control for the ‘litter effect’ — this needs to change
Anyone who uses multiple animals from a small number of litters to increase sample size is making a serious mistake. The similarities within individual litters will heavily skew the results.
Few autism researchers control for the ‘litter effect’ — this needs to change
Length matters: Disease implications for long genes
A gene’s length may influence its expression, and this has implications for autism, which tends to be linked to particularly long genes, says Mark Zylka.
Length matters: Disease implications for long genes
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Grant review needs reform. How about we add an element of chance?
A process that uses a lottery system saves time, reduces strategic resubmission and accepts that, above a quality threshold, luck has always played a part in science funding.
Grant review needs reform. How about we add an element of chance?
A process that uses a lottery system saves time, reduces strategic resubmission and accepts that, above a quality threshold, luck has always played a part in science funding.
Fly neurons carry molecular signatures of their origins
The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.
Fly neurons carry molecular signatures of their origins
The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.