Sarkis Mazmanian
Professor of microbiology
California Institute of Technology
From this contributor
Remembering Paul Patterson (1944-2014)
Paul H. Patterson, a transformative figure in autism research, died on 25 June. His groundbreaking discoveries advanced novel paradigms in neuroscience and immunology, and introduced concepts that will continue to be developed by researchers worldwide.
The case for using ‘prebiotics’
Prebiotics — nutrients that promote the growth of some beneficial gut bacteria — can influence brain chemistry and behavior. New findings suggest prebiotics as treatments for people with neurological disorders, say Sarkis Mazmanian and Gil Sharon.
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Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests
Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.
Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests
Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.
Microglia scoop out garbage from inside neurons
Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.
Microglia scoop out garbage from inside neurons
Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.