Locus coeruleus

Recent articles

Research image of locus coeruleus.

Brain’s blue spot possesses unexpected structure-function ties

The spatial arrangement of neurons in the locus coeruleus of mice corresponds with the cells’ targets across the brain, according to a new study.

By Holly Barker
25 May 2026 | 4 min read

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch

The brain’s quiet conductor: How hidden cells fine-tune arousal

New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.

By Mac Shine
7 May 2025 | 59 min watch
Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read
Micrograph comparing locus coeruleus of 16p11.2 mutant mice and control mice show less active noradrenergic neurons in mutant mice.

Circuit flaw underlies motor learning issues in autism mouse model

Mice missing a copy of chromosomal region 16p11.2 are slow to learn motor tasks and have dysfunction in a brain circuit associated with stress and movement, according to a new study. Normalizing this circuit's activity corrects the learning deficit.

By Peter Hess
12 April 2021 | 4 min read

Explore more from The Transmitter

Researcher examining butterfly in lab.

Finally, a new route for the magnetic-sense field

Researchers have dueled for years over how the magnetic sense works. New data from monarch butterflies could finally help settle the debate.

By Calli McMurray
11 September 2026 | 16 min read
Child sitting on confetti-covered ground, wearing noise-cancelling headphones.

Sensory over-responsivity tied to autism, anxiety but not other conditions

Negative reactions to sensations track with certain neurodevelopmental traits in more than 15,000 children—pointing to shared neurobiological roots.

By Diana Kwon
10 September 2026 | 5 min read

Neuromechanical models deepen our understanding of animal motor control

Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.

By Auke Ijspeert
9 September 2026 | 0 min watch