Neurogenesis
Recent articles
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.

Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.
Head size parts autism into two major subtypes
An imbalance in the number of excitatory neurons in early brain development may account for the difference.

Head size parts autism into two major subtypes
An imbalance in the number of excitatory neurons in early brain development may account for the difference.
Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.

Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.
Rare autism-linked mutation starves growing neurons of essential nutrients
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

Rare autism-linked mutation starves growing neurons of essential nutrients
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
Immune molecule alters cellular makeup of human brain organoids
The changes may help explain the link between maternal infection and autism, though more research is needed.

Immune molecule alters cellular makeup of human brain organoids
The changes may help explain the link between maternal infection and autism, though more research is needed.
Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.

Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.
Autism-tied gene ZNF462 keeps developing neurons on track
The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.

Autism-tied gene ZNF462 keeps developing neurons on track
The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.
Lab-grown ‘embryoids’ offer new window into gene-trait relationships
The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.

Lab-grown ‘embryoids’ offer new window into gene-trait relationships
The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.
Explore more from The Transmitter
‘Digital humans’ in a virtual world
By combining large language models with modular cognitive control architecture, Robert Yang and his collaborators have built agents that are capable of grounded reasoning at a linguistic level. Striking collective behaviors have emerged.
‘Digital humans’ in a virtual world
By combining large language models with modular cognitive control architecture, Robert Yang and his collaborators have built agents that are capable of grounded reasoning at a linguistic level. Striking collective behaviors have emerged.
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?