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Autism experts venture to set the narrative for INSAR, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 20 April.

Opportunity to opine: As the autism research community gears up for the annual meeting of the International Society for Autism Research, which starts tomorrow in Prague, Czech Republic, prominent researchers are expressing their views in published editorials. Geraldine Dawson of Duke University articulates the tensions within the autism community: Some say researchers should prioritize supports and services for autistic people, whereas others advocate for putting an emphasis on genetic research for those with high support needs. Lester Liao of McGill University and Eric Fombonne of Oregon Health & Science University argue that overdiagnosis of autism leads to harm. Boston College’s Kristen Bottema-Beutel reveals ableist perspectives that she says permeate federal guidance on autism in the United States.  

Autism research spotted this week: 

  • “Scaffold protein SHANK3 regulates endothelial cell motility and tissue mechanics” bioRxiv
Research image of human endothelial cells grown in vitro.
Changing shape: Human endothelial cells grown in vitro have a polygonal forms (left panel), but silencing the SHANK3 gene leads to more elongated cells (middle and right panels).
  • “Molecular dynamics of Brodmann Area 22 in development and autism” bioRxiv
  • “Newborn IgG and IgM antibodies to maternal SARS-CoV-2 infection in pregnancy and child neurodevelopmental outcomes” Brain, Behavior, and Immunity
  • “Genetic comparisons of interleukin-17 reveal a framework for complex signaling evolution” bioRxiv

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