Striatum
Recent articles
What to do when traditional mechanistic approaches no longer work
Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”
What to do when traditional mechanistic approaches no longer work
Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Structure of striatum varies by sex in autistic children
The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.
Structure of striatum varies by sex in autistic children
The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
Explore more from The Transmitter
Amid funding uncertainty, graduate neuroscience programs in the U.S. adapt
The Transmitter surveyed 50 graduate program directors to learn how they’re faring. Securing labs for new students is one of the greatest concerns.
Amid funding uncertainty, graduate neuroscience programs in the U.S. adapt
The Transmitter surveyed 50 graduate program directors to learn how they’re faring. Securing labs for new students is one of the greatest concerns.
The changing nature of the neuroscience Ph.D.
The best science can only be sustained by a steady influx of early-stage scientists and the innovative ideas they bring, says Diane Lipscombe. She reflects on the loss of international students, the value of training grants, and the challenges that lie ahead for graduate education.
The changing nature of the neuroscience Ph.D.
The best science can only be sustained by a steady influx of early-stage scientists and the innovative ideas they bring, says Diane Lipscombe. She reflects on the loss of international students, the value of training grants, and the challenges that lie ahead for graduate education.
Rethinking neuroscience graduate education in the age of AI
What knowledge from traditional training protocols needs to be maintained, what can be discarded, and what new types of training should be introduced? Six neuroscientists weigh in.
Rethinking neuroscience graduate education in the age of AI
What knowledge from traditional training protocols needs to be maintained, what can be discarded, and what new types of training should be introduced? Six neuroscientists weigh in.