Striatum

Recent articles

Illustration of a person standing in a crumbling room with papers and strings on the wall, a fallen chair, and a lamp.

What to do when traditional mechanistic approaches no longer work

Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”

By Bence Ölveczky
19 October 2026 | 8 min read
Research image of human thalamus.

Among brain changes studied in autism, spotlight shifts to subcortex

The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.

By Holly Barker
11 December 2025 | 5 min read
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 4 min read
Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Child playing with blocks.

Structure of striatum varies by sex in autistic children

The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.

By Holly Barker
27 February 2025 | 4 min read
Research image of circuits emerging from striosomes in the striatum.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

By Claudia López Lloreda
24 January 2025 | 4 min read
Illustration of cranes attempting to assemble a structure out of very small black squares.

Reconstructing dopamine’s link to reward

The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

By Angie Voyles Askham
13 September 2024 | 18 min read
Research image of neurons in mice.

Skewed signaling in striatum may spawn repetitive behaviors

Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.

By Holly Barker
6 September 2023 | 3 min read
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read

Autism’s ties to the cell skeleton

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

By Giorgia Guglielmi
22 June 2023 | 0 min watch

Explore more from The Transmitter

A crow looking at a screen showing a circle of white dots on a black background.

Crows have brains ‘in the fast lane’

The birds accurately complete decision-making tasks twice as fast as primates, although their endbrains look considerably different.

By Sarah Thau
22 October 2026 | 4 min read
A boy manipulates blocks at a table while sitting across from a woman taking notes.

Prevalence of profound autism declines with new definition

The updated, more precise definition used in a CDC study includes adaptive scores.

By Brianna Abbott
22 October 2026 | 5 min read

Is it time for neuroscience to shift its focus from a computational mind to a navigating mind?

Andrea Hiott explains her navigational approach to the mind, and why now is the time to embrace seemingly paradoxical findings in neuroscience.

By Paul Middlebrooks
21 October 2026 | 1 min read