Striatum
Recent articles
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Structure of striatum varies by sex in autistic children
The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.
Structure of striatum varies by sex in autistic children
The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
One-rosette technique grows well-organized organoids
The method yields complex organoids that more closely mimic embryonic brain development than do those cultured in other ways.
One-rosette technique grows well-organized organoids
The method yields complex organoids that more closely mimic embryonic brain development than do those cultured in other ways.
Explore more from The Transmitter
Autism-linked genes alter sleep behavior, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 13 April.
Autism-linked genes alter sleep behavior, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 13 April.
This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli
A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.
This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli
A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.
Why neural foundation models work, and what they might—and might not—teach us about the brain
These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?
Why neural foundation models work, and what they might—and might not—teach us about the brain
These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?