Synapses

Recent articles

Research image of X-linked RNAs in male mice.

Noncoding RNA sways core autism traits in mice

Small deletions in an X-linked RNA alter social and repetitive behaviors in male mice without broadly affecting learning or memory.

By Giorgia Guglielmi
11 June 2026 | 4 min read
Headshots of the 2026 Kavli Prize in Neuroscience winners.

Four protein synthesis pioneers win Kavli Prize in Neuroscience

Their research revealed how neurons synthesize proteins in previously unrecognized places.

By Alissa de Chassey
10 June 2026 | 4 min read
Research image of cell-surface protein LPHN2.

‘Push-pull’ recipe for neural wiring used in multiple brain regions

A versatile pair of proteins steers neurons toward their targets and helps establish the brain’s sensory maps, new studies suggest.

By Holly Barker
5 June 2026 | 5 min read
Illustration of a synapse.

Neuroscience needs single-synapse studies

Studying individual synapses has the potential to help neuroscientists develop new theories, better understand brain disorders and reevaluate 70 years of work on synaptic transmission plasticity.

By Seth Grant
17 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Research image of human neurons transplanted into mouse cortices.

Protein tug-of-war controls pace of synaptic development, sets human brains apart

Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

By Holly Barker
23 October 2025 | 7 min read
Research image of SCN2A neurons.

Boosting SCN2A expression reduces seizures in mice

A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

By Charles Q. Choi
9 October 2025 | 5 min read
Research image of axons forming a path into brain metastases of small-cell lung cancer, integrating tumors into the brain.

Neurons fuel lung tumors that have spread to brain

Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.

By Sarah DeWeerdt
6 October 2025 | 6 min read
Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans

By Holly Barker
29 August 2025 | 7 min read
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 6 min read

Explore more from The Transmitter

Mother mouse and her offspring.

Maternity induces lasting gene-expression changes in mouse brains

The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.

By Amber Dance
12 June 2026 | 5 min read
Map of socioeconomic opportunity in the United States next to visualizations of functional connectivity and structure in sensory and motor cortices.

IQ’s link to brain structure, function in children may be a mirage

A child’s socioeconomic status, screen time and amount of sleep all show stronger associations with measures of brain structure and function, according to an imaging study of nearly 12,000 9- to 10-year-olds.

By Natalia Mesa
11 June 2026 | 5 min read
Photo collage of Tempest McDonald.

When autistic kids grow up, Chapter 2: “You need to go to college”

With just a high school equivalency degree and struggling as a single mother, Tempest McDonald is forced to shift her priorities.

By Brady Huggett
11 June 2026 | 28 min listen