Synapses

Recent articles

Research image of cursor movement from high gamma activity.

Recording warning: Common brain signal may be misunderstood

High gamma activity in electrophysiologic recordings reflects widespread neural activity, not merely local firing, as previously thought.

By Claudia López Lloreda
30 June 2026 | 5 min read
Connexiohuman Connexin 26 dodecamer at 90mmHg PCO2, pH7.4

Designer synapses edit brain circuits in living animals

The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.

By Simon Makin
23 June 2026 | 5 min read
Research image of X-linked RNAs in male mice.

Noncoding RNA sways core autism traits in mice

Small deletions in an X-linked RNA alter social and repetitive behaviors in male mice without broadly affecting learning or memory.

By Giorgia Guglielmi
11 June 2026 | 4 min read
Headshots of the 2026 Kavli Prize in Neuroscience winners.

Four protein synthesis pioneers win Kavli Prize in Neuroscience

Their research revealed how neurons synthesize proteins in previously unrecognized places.

By Alissa de Chassey
10 June 2026 | 4 min read
Research image of cell-surface protein LPHN2.

‘Push-pull’ recipe for neural wiring used in multiple brain regions

A versatile pair of proteins steers neurons toward their targets and helps establish the brain’s sensory maps, new studies suggest.

By Holly Barker
5 June 2026 | 5 min read
Illustration of a synapse.

Neuroscience needs single-synapse studies

Studying individual synapses has the potential to help neuroscientists develop new theories, better understand brain disorders and reevaluate 70 years of work on synaptic transmission plasticity.

By Seth Grant
17 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Research image of human neurons transplanted into mouse cortices.

Protein tug-of-war controls pace of synaptic development, sets human brains apart

Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

By Holly Barker
23 October 2025 | 7 min read
Research image of SCN2A neurons.

Boosting SCN2A expression reduces seizures in mice

A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

By Charles Q. Choi
9 October 2025 | 5 min read
Research image of axons forming a path into brain metastases of small-cell lung cancer, integrating tumors into the brain.

Neurons fuel lung tumors that have spread to brain

Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.

By Sarah DeWeerdt
6 October 2025 | 6 min read

Explore more from The Transmitter

Research image of mitochondrial activity in the mouse amygdala and hippocampus.

The fast-expanding repertoire of mitochondria in the brain

More than cellular powerhouses, these organelles also seem to help synapses communicate, support memory formation and even shape behavior.

By Giorgia Guglielmi
3 July 2026 | 7 min read
Two fingers turning a small dial.

When autistic kids grow up, Chapter 5: The war dial

“You have to reshape the whole system.” Tempest McDonald earns a measure of peace.

By Brady Huggett
2 July 2026 | 42 min listen
Red note stuck in a stack of paper.

Scientists decry conference’s use of hidden prompts to snare AI peer reviews

The invisible messages, which instruct large language models to use telltale phrases in a peer-review report, are effective in catching artificial-intelligence misuse but also erode trust, some say.

By Dalmeet Singh Chawla
1 July 2026 | 4 min read