Brain Inspired

Recent articles

This podcast, hosted by Paul Middlebrooks, features in-depth conversations with neuroscientists studying natural and artificial intelligence, philosophy, consciousness and other related areas.

Can neuroscientists decode memories solely from a map of synaptic connections?

Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns.

By Paul Middlebrooks
17 December 2025 | 1 min read

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read

Does AI understand what it produces? Henk de Regt explores how we might assess understanding in machines and humans

Building on his philosophy of how scientists understand what they work on, de Regt is extending his approach to test understanding in machines.

By Paul Middlebrooks
19 November 2025 | 1 min read

Daniel Nicholson discusses how Schrödinger’s book ‘What is Life?’ shaped years of biology, research

Combing through historical archives, Nicholson discovered what drove Erwin Schrödinger to pen “What Is Life,” his famous "little book": Schrödinger feared that new discoveries in quantum physics would influence how we think about free will.

By Paul Middlebrooks
5 November 2025 | 1 min read

Vicente Raja brings ecological psychology concepts to neuroscience

He suggests neuroscientists should pay more attention to the principles of Gibsonian ecological psychology, such as affordances, ecological information and resonance, to better explain perception and action.

By Paul Middlebrooks
22 October 2025 | 99 min listen

Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’

He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.

By Paul Middlebrooks
8 October 2025 | 1 min read

Ann Kennedy explains the theoretical neuroscience of survival behaviors

The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.

By Paul Middlebrooks
24 September 2025 | 1 min read

Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales

Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.

By Paul Middlebrooks
10 September 2025 | 1 min read

Xaq Pitkow shares his principles for studying cognition in our imperfect brains and bodies

Pitkow discusses how evolution's messy constraints shape optimal brain algorithms, from Bayesian inference to ecological affordances.

By Paul Middlebrooks
27 August 2025 | 1 min read

Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders

Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.

By Paul Middlebrooks
13 August 2025 | 1 min read

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New organoid atlas unveils phenotypic signatures of multiple neurodevelopmental conditions

The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.

By Diana Kwon
17 December 2025 | 4 min read
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AI-assisted coding: 10 simple rules to maintain scientific rigor

These guidelines can help researchers ensure the integrity of their work while accelerating progress on important scientific questions.

By Russell Poldrack
16 December 2025 | 7 min read
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Glutamate receptors, mRNA transcripts and SYNGAP1; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 15 December.

By Jill Adams
16 December 2025 | 2 min read

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