Dup15q 2013

Recent articles

Spectrum from The Transmitter.

Duplication of chromosome 15 region mirrors autism

People with autism and those with duplications of the 15q11-13 chromosomal region share a distinctive pattern of gene expression in the brain, according to unpublished research presented Friday at the Dup15q Alliance Scientific Meeting in Sacramento, California.

By Sarah DeWeerdt
23 September 2013 | 3 min read
Spectrum from The Transmitter.

Gene expression in neurons may not match number of copies

Neurons derived from individuals who carry extra copies of an autism-linked chromosomal region have gene expression patterns that are unexpectedly similar to those of neurons with deletions of the region. The unpublished findings were presented Thursday at the Dup15q Alliance Scientific Meeting in Sacramento, California.

By Sarah DeWeerdt
23 September 2013 | 4 min read
Spectrum from The Transmitter.

Mouse model hints at autism gene’s role in nucleus

Mice that express elevated levels of an autism-linked gene in the nucleus of neurons show social and communication problems, according to unpublished research presented Thursday at the Dup15q Alliance Scientific Meeting in Sacramento, California.

By Sarah DeWeerdt
20 September 2013 | 3 min read

Explore more from The Transmitter

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read

Psychedelics meta-analysis retracted after authors request ‘significant changes’

While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.

By Marta Hill
11 June 2025 | 2 min read
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 5 min listen