Oxidative stress
Recent articles
Neurons tune electron transport chain to survive onslaught of noxious stimuli
Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.
 
            
            Neurons tune electron transport chain to survive onslaught of noxious stimuli
Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.
Null and Noteworthy: Metacognition, balovaptan bust, pattern recognition
This month, we pore over null results from a study of the accuracy of emotion recognition skills in autistic people, clinical trials of a vasopressin drug called balovaptan, and an analysis of ‘systemizing’ abilities in autistic children.
 
            
            Null and Noteworthy: Metacognition, balovaptan bust, pattern recognition
This month, we pore over null results from a study of the accuracy of emotion recognition skills in autistic people, clinical trials of a vasopressin drug called balovaptan, and an analysis of ‘systemizing’ abilities in autistic children.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
Meet the ‘mitomaniacs’ who say mitochondria matter in autism
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
 
            
            Meet the ‘mitomaniacs’ who say mitochondria matter in autism
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
Autism mutation may disrupt brain structure by disabling mitochondria
Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.
 
            
            Autism mutation may disrupt brain structure by disabling mitochondria
Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.
New tools strengthen old link between autism, mitochondria
Variants of some mitochondrial genes may contribute to autism — in some cases, by teaming up with genes in the nucleus.
 
            
            New tools strengthen old link between autism, mitochondria
Variants of some mitochondrial genes may contribute to autism — in some cases, by teaming up with genes in the nucleus.
Obesity, diabetes in mother up autism risk for child
The combination of obesity and diabetes in a pregnant woman substantially increases the likelihood that her child will have autism.
 
            
            Obesity, diabetes in mother up autism risk for child
The combination of obesity and diabetes in a pregnant woman substantially increases the likelihood that her child will have autism.
Short chromosome caps may up autism risk in families
Telomeres, the structures at the tips of chromosomes, tend to be unusually short in people with autism and their immediate family members.
 
            
            Short chromosome caps may up autism risk in families
Telomeres, the structures at the tips of chromosomes, tend to be unusually short in people with autism and their immediate family members.
Diabetes during pregnancy ups child’s autism risk
Children born to women who develop diabetes during the first or second trimester of pregnancy increase their risk of autism by 42 percent.
 
            
            Diabetes during pregnancy ups child’s autism risk
Children born to women who develop diabetes during the first or second trimester of pregnancy increase their risk of autism by 42 percent.
Genetics: Gene variants modulate Rett symptoms
A single gene mutation leads to Rett syndrome, but other variants may modify the severity of an individual's symptoms, according to a study published 28 February in PLoS One.
 
            
            Genetics: Gene variants modulate Rett symptoms
A single gene mutation leads to Rett syndrome, but other variants may modify the severity of an individual's symptoms, according to a study published 28 February in PLoS One.
Explore more from The Transmitter
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
 
            
            Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Image integrity issues create new headache for subarachnoid hemorrhage research
First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.
 
            
            Image integrity issues create new headache for subarachnoid hemorrhage research
First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.
Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.
 
            
            Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.