Astrocytes

A research image showing astrocytes and neurons

‘SNAP’ dance of astrocytes and neurons falls out of step with age, disease

The findings add to growing evidence that astrocytes are star players in cognition.

By Laura Dattaro
6 March 2024 | 6 min read
Image of excitatory synapses in mouse brains.
Astrocytes Microphone

Dispute erupts over role of sticky proteins in astrocytes

But multiple independent researchers say they are not convinced by its results, which fail to confirm high-profile findings from 2017.

By Lauren Schenkman
10 July 2023 | 9 min listen
Research image of gene-edited mouse liver cells compared to controls.

Latest ‘prime-editing’ tools tackle delivery, safety issues

The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.

By Charles Q. Choi
27 June 2023 | 5 min read
Research image of neurons and astrocytes.

Astrocytes fuel erratic firing in fragile X neurons

A shift in astrocyte secretions may explain the atypical firing patterns of neurons derived from people with fragile X syndrome.

By Lauren Schenkman
10 May 2023 | 5 min read
Autism researcher Veronica Martinez Cereno holds a brain in her lab.

Beyond the bench: At school with Verónica Martínez Cerdeño

Spectrum caught up with the University of California, Davis professor about her passion for volunteering in underserved schools, birding and fossil-hunting.

By Lauren Schenkman
1 May 2023 | 6 min read
Image of organoids modeling CDKL5 deficiency disorder.
Spectrum Microphone

Organoids identify potential therapies, circuit flaws for autism-linked syndromes

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

By Peter Hess
21 November 2022 | 3 min read
Single astrocyte on black background.

Mouse studies cast astrocytes as stars of sensory perception

Data from two separate research teams suggest the cells are key to sensory hypersensitivity in fragile X syndrome.

By Sarah DeWeerdt
13 November 2022 | 4 min read
six images of astrocytes

How star cells’ secretions may stunt neurons: Q&A with Nicola Allen

Non-neuronal brain cells called astrocytes secrete proteins that seem to hamper the growth of neurons in people with autism-related syndromes. These proteins could be new drug targets, Allen says.

By Lauren Schenkman
26 September 2022 | 7 min read

Portrait of a research field: astrocytes in autism

Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.

By Lauren Schenkman
14 July 2022 | 14 min read

Glial cells star in autism-linked gene expression analysis

Many genes linked to autism are switched on in the brain's glia, cells that help neurons develop and synapses form.

By Lauren Schenkman
15 December 2021 | 4 min read

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Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
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Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

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By Cathleen O’Grady
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