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Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders

Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.

By Paul Middlebrooks
13 August 2025 | 107 min watch

In this “Brain Inspired” episode, Paul Middlebrooks is joined by Chris Rozell, director of the Institute for Neuroscience, Neurotechnology, and Society at the Georgia Institute of Technology and principal investigator of the Structured Information for Precision Neuroengineering Lab. Rozell discusses a new biomarker to help clinicians and psychiatrists care for patients with treatment-resistant depression. His team uses deep brain stimulation electrodes to record local field potentials and generative explainable AI to predict patients’ recovery trajectories. Rozell also shares his personal backstory and why community and support are so important in the scientific setting.

Read the transcript.

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