Psychiatric disorders

Recent articles

The brain’s quiet conductor: How hidden cells fine-tune arousal

New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.

By Mac Shine
7 May 2025 | 59 min watch
Tiger in a brain scanner.

Lions and tigers and bears: Long-lived zoo animals offer a promising venue to study mental health and neurodegenerative disorders

These animals’ lifestyles often mirror those of people, making them a more relevant milieu than lab mice for determining how environmental factors influence mental health and cognitive decline. Studying them could improve animal welfare in the process.

By Christine J. Charvet
17 March 2025 | 5 min read
Illustration of two silhouettes overlaid by opaque square panels.

Why hasn’t genetics taught us more about schizophrenia?

Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

By Joshua R. Sanes
18 February 2025 | 8 min read
Illustration of a body, brain visible through a transparent head, looking at orange circles over its hands.

Rethinking mental health: The body’s impact on the brain

Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

By Georgia E. Hodes
11 February 2025 | 6 min read
Illustration of a sparkly brain.

What, if anything, makes mood fundamentally different from memory?

To better understand mood disorders—and to develop more effective treatments—should we target the brain, the mind, the environment or all three?

By Nicole Rust
8 April 2024 | 8 min read
An image of the DSM-5-TR where the S is replaced with a dollar sign

Physicians who oversaw diagnostic manual’s revision had pharma funding

Of the 92 U.S.-based physicians who worked on the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, 55 of them have collectively received millions of dollars from drug and device companies, new research shows.

By Elissa Welle
10 January 2024 | 5 min read
A hand points to an illustration on a chalkboard.

From a scientist’s perspective: The Transmitter’s top five essays in 2023

From big-picture debates about theories and terms to practical tips for teaching and writing, our favorite expert-written articles offer a glimpse into what neuroscientists are thinking.

By The Transmitter
25 December 2023 | 3 min read
Illustration of a meteorologist pointing to an aerial view of clouds swirling over a brain-shaped land mass.

Is the brain uncontrollable, like the weather?

The brain may be chaotic. Does that mean our efforts to control it are doomed?

By Nicole Rust
18 December 2023 | 10 min read

Explore more from The Transmitter

Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Seattle skyline.

Reporter’s notebook: Highlights from INSAR 2025

The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.

By Daisy Yuhas
15 May 2025 | 5 min read
A researcher stands at the top of a staircase that leads to nowhere.

NIDA shutters diversity fellowship program, axes active awards

It’s unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.

By Calli McMurray
14 May 2025 | 4 min read