Brain size
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Common genetic variants shape the structure of the cortex
Head size parts autism into two major subtypes
An imbalance in the number of excitatory neurons in early brain development may account for the difference.
Head size parts autism into two major subtypes
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Change of heart and mind: Autism’s ties to cardiac defects
Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.
Genetic background sways effects of autism-linked mutation
Autism-related genes converge on microglia and dopamine in zebrafish
The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
Autism-related genes converge on microglia and dopamine in zebrafish
Rare autism-linked mutation starves growing neurons of essential nutrients
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
Rare autism-linked mutation starves growing neurons of essential nutrients
Zebrafish point to new gene involved in brain overgrowth, autism
The gene, YTHDF2, has not previously been linked to autism.
Zebrafish point to new gene involved in brain overgrowth, autism
Different forms of autism have opposite problems with brain precursor cells
The cells’ altered proliferation rates hint at ways to diagnose and potentially treat autism earlier.
Different forms of autism have opposite problems with brain precursor cells
Novel gene linked to brain size in autistic people
The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.
Novel gene linked to brain size in autistic people
Explore more from The Transmitter
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.