Circuits
Recent articles
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.

Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.

Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
Explore more from The Transmitter
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?
To accelerate the study of neurodevelopment, we need a transdiagnostic framework
Our tendency to focus on one condition at a time likely silos expertise and services—and obscures critical connections across diagnostic categories.

To accelerate the study of neurodevelopment, we need a transdiagnostic framework
Our tendency to focus on one condition at a time likely silos expertise and services—and obscures critical connections across diagnostic categories.