Warming seas disrupt the function of neurons — and could seed permanent changes in marine species, according to studies of a circuit that controls digestion in crustaceans.
Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.
After 10 years of work, Neurona may have the data to quiet its skeptics. But its ongoing clinical trial will be the ultimate test.
The underlying regional neurobiology of the conditions may differ from person to person.
The map, by far the largest one of an entire brain to date, contains 130,000 neurons and 53 million synapses.
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.
The map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.