Addiction

Recent articles

A central circle displays patterns in genetic data.

This paper changed my life: Transformative work in addiction neuroscience

A 2011 Nature study found that loss of a nicotinic receptor subunit leads to increased nicotine intake in mice. The work set the standard for how to functionally validate genetic association study findings in neuroscience.

By Jibran Khokhar
16 September 2026 | 6 min read
Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 4 min read
Illustration of clinicians, a pill bottle, a speech bubble and shadowy figures.

Neuroscientists need to do better at explaining basic mental health research

The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.

By Omar Abubaker, Karla Kaun, Eric J. Nestler
21 January 2025 | 7 min read
A photograph of researcher Aya Osman

Striking a pose with Aya Osman

The neuroscientist and part-time fashion model opens up about the people who inspire her; her interest in science communication; and how she once ended up on a stage with Channing Tatum.

By Angie Voyles Askham
31 May 2024 | 7 min read
A diagram of green neurnons

Cocaine, morphine commandeer neurons normally activated by food, water in mice

Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

By Lauren Schenkman
8 May 2024 | 5 min read
Research image of microglia in rats.

Temperament is innate but hackable, animal studies suggest

Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.

By Holly Barker
23 January 2024 | 8 min read

Explore more from The Transmitter

Mouse wearing a white, cube-like device on its head.

WILD platform levels up ability to record brain activity, behavior in nature

The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.

By Simon Makin
29 October 2026 | 6 min read

The relationship between structure and function in cortical networks

Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.

By Gaute Einevoll
28 October 2026 | 138 min listen
Stock image of branching dendrites.

How brains prevent ‘catastrophic forgetting’

Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.

By Natalia Mesa
28 October 2026 | 6 min read