Gerald Crabtree
Professor of Pathology and Developmental Biology
Stanford University
From this contributor
Emerging importance of chromatin in autism risk
Sequencing studies over the past few years have made a dramatic and unexpected discovery: Many of the mutations in individuals with autism are in genes that regulate chromatin, which helps package DNA in the cell nucleus, say Gerald Crabtree and Aryaman Shalizi.
Emerging importance of chromatin in autism risk
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Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.