James Gusella
Professor
Massachusetts General Hospital and Harvard Medical School
From this contributor
No ‘ideal’ tissue for gene expression studies of autism
Researchers should investigate a broad spectrum of human- and animal-derived tissues to fully capture the complexity of autism, say Michael Talkowski and James Gusella.
No ‘ideal’ tissue for gene expression studies of autism
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Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Polarized cortical organoids mimic the brain’s regional organization
The organoids show region-specific gene-expression changes that match those observed during fetal development.
Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests
Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.
Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests
Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.
Microglia scoop out garbage from inside neurons
Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.
Microglia scoop out garbage from inside neurons
Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.