Karthik Shekhar is John F. Heil Jr. Professor in the chemical and biomolecular engineering department at the University of California, Berkeley. His laboratory is cross-affiliated with neuroscience, vision science and the Lawrence Berkeley Laboratory. His interests are at the interface of neuroscience, genomics and applied mathematics, and his group uses both experimental and computational approaches to understand how diverse types of neurons in the brain develop and evolve, and how they become selectively vulnerable during diseases. He has received the NIH Pathway to Independence Award, the Hellman Fellowship and the McKnight Fellowship in Neuroscience. He also recently received the Donald E. Noyce Prize for Excellence in Undergraduate Teaching.

Karthik Shekhar
Assistant professor of chemical and biomolecular engineering
University of California, Berkeley
From this contributor
Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.

Building a brain: How does it generate its exquisite diversity of cells?
Explore more from The Transmitter
Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.
Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.

Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.
Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.