Diffusion tensor imaging

MRI scan of a 2-year-old child.

Mapping genetic influences on the infant brain: A chat with Rebecca Knickmeyer

Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.

By Laura Dattaro
27 February 2023 | 6 min read
Structural anomalies (purple and blue) in the brains of babies with autism at 6 months (bottom row) become more widespread by 12 months (top row).

Weak ‘wiring’ in infant brains augurs severe autism features

Babies who are later diagnosed with autism may show aberrant connections between some brain regions in their first year of life.

By Nicholette Zeliadt
21 August 2017 | 4 min read

Brain scans of babies reveal how nerve tracts mature

Bundles of nerve fibers that bridge brain areas develop rapidly during the first six months of life. Fibers that connect language regions mature more slowly than those linking motor regions.

By Katie Moisse
13 May 2017 | 3 min read

Common brain signature marks autism, attention deficit

Children with autism, attention deficit hyperactivity disorder or obsessive-compulsive disorder all show similar disruptions in brain structure.

By Ann Griswold
8 August 2016 | 3 min read

Motor troubles in Angelman may stem from nerve fiber anomaly

Unusually thin nerve fibers in the brain may underlie the motor difficulties seen in children with Angelman syndrome, an autism-related condition.

By Nicholette Zeliadt
1 August 2016 | 5 min read

Tightly folded autism brain tied to dense neural connections

An intricately pleated brain may underlie the highly organized connections between nearby neurons in people with autism.

By Jessica Wright
2 June 2016 | 5 min read

Extra-thick connections mark brains of toddlers with autism

The brains of young children with autism show abnormally dense connections involving the frontal lobe. The excess wiring may disrupt the development of social and language circuits.

By Rachel Zamzow
18 September 2015 | 4 min read

Thick bridge of nerves may signal autism in infancy

The bundle of nerves that connects the brain’s two hemispheres is abnormally thick in infants who are later diagnosed with autism. The broader the bundle, called the corpus callosum, the more severe a child’s symptoms.

By Nicholette Zeliadt
4 June 2015 | 4 min read

Brain structure abnormalities predict repetitive behaviors

Among babies who go on to receive a diagnosis of autism at age 2, alterations in brain structures forecast the severity of repetitive behaviors. The preliminary results were presented Saturday at the 2015 International Meeting for Autism Research in Salt Lake City, Utah.    

By Nicholette Zeliadt
19 May 2015 | 3 min read

Head movement in scanners skews brain measurements

Even small movements of the head during magnetic resonance imaging can lead to spurious measurements of brain structures, according to a new study.

By Nicholette Zeliadt
9 January 2015 | 3 min read

Explore more from The Transmitter

Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read