Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Research image of myelinated axons.

Oligodendrocytes need mechanical cues to myelinate axons correctly

Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.

By Calli McMurray
11 February 2026 | 5 min read

Modern AI is simply no match for the complexity likely required for harboring consciousness, says Jaan Aru

He argues that our brain’s computations are of a completely different nature than any artificial intelligence because they take place across many spatial and temporal scales and are inextricably entwined with biological materials.

By Paul Middlebrooks
11 February 2026 | 1 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Interneurons’ role in epilepsy, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 9 February.

By Jill Adams
10 February 2026 | 1 min read

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