Fragile X syndrome
Recent articles
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Understanding fragile X syndrome
Just in time for Fragile X Awareness Month, The Transmitter rounds up notable coverage.
Understanding fragile X syndrome
Just in time for Fragile X Awareness Month, The Transmitter rounds up notable coverage.
Noisy brain may underlie some of autism’s sensory features
Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.
Noisy brain may underlie some of autism’s sensory features
Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
‘Social touch’ responses in mice gauged with unprecedented control
A new tool could help decipher the brain circuits underlying aversion to social touch, which is common in people with autism.
‘Social touch’ responses in mice gauged with unprecedented control
A new tool could help decipher the brain circuits underlying aversion to social touch, which is common in people with autism.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Skewed signaling in striatum may spawn repetitive behaviors
Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.
Neuronal deafness to stress may add to protein surplus in fragile X
A protective pathway that pauses protein synthesis is muted in a mouse model of fragile X syndrome, according to a new study.
Neuronal deafness to stress may add to protein surplus in fragile X
A protective pathway that pauses protein synthesis is muted in a mouse model of fragile X syndrome, according to a new study.
Is excess brain fluid an early marker of autism?
Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.
Is excess brain fluid an early marker of autism?
Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.
Prenatal exposures; Angelman trial suspension; autistic adult well-being
This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.
Prenatal exposures; Angelman trial suspension; autistic adult well-being
This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.
Explore more from The Transmitter
How will neuroscience training need to change in the future?
Training in computational neuroscience, data science and statistics will need to expand, say many of the scientists we surveyed. But that must be balanced with a more traditional grounding in the scientific method and critical thinking. Researchers noted that funding concerns will also affect training, especially for people from underrepresented groups.
How will neuroscience training need to change in the future?
Training in computational neuroscience, data science and statistics will need to expand, say many of the scientists we surveyed. But that must be balanced with a more traditional grounding in the scientific method and critical thinking. Researchers noted that funding concerns will also affect training, especially for people from underrepresented groups.
The leaders we have lost
Learn more about the lives and legacies of the neuroscientists who passed away between 2023 and 2025.
The leaders we have lost
Learn more about the lives and legacies of the neuroscientists who passed away between 2023 and 2025.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.