Hindsight is 2020: The year in review

Recent articles

top-down view of the mouse brain

2020 in research images

Feast your eyes on glowing glia and organoids; high-resolution, digital renditions of mouse brains; fluorescent beads passing through zebrafish guts and more.

By Spectrum
23 December 2020 | 2 min read
researcher facing off with the coronavirus.

Rewind: Spectrum’s best from 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

By Spectrum
23 December 2020 | 5 min read
Lab scene during COVID 19 pandemic.

Inside the reporter’s notebook: Dispatches from 2020

Spectrum's staff couldn't report on the ground this year — with no lab visits, sit-down interviews or in-person conferences to attend — but we observed a lot of changes from our computer screens.

By Spectrum
23 December 2020 | 4 min read
Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Hot topics in autism research, 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

By Spectrum
23 December 2020 | 8 min read
White lab mouse sitting in a gloved hand.

Notable papers in autism research, 2020

Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

By Spectrum
23 December 2020 | 4 min read

Explore more from The Transmitter

Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Autism-linked genes alter sleep behavior, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 13 April.

By Jill Adams
14 April 2026 | 2 min read
Illustration of a monkey pushing a button.

This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli

A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.

By Erin Calipari
14 April 2026 | 5 min read
Illustration of a sheet of paper with a topography map-like pattern on it.

Why neural foundation models work, and what they might—and might not—teach us about the brain

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?

By Juan Gallego
13 April 2026 | 8 min read