Hippocampus
Recent articles
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.
Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.
What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.
What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”
Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”
Alison Preston explains how our brains form mental frameworks for interpreting the world
Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.
Alison Preston explains how our brains form mental frameworks for interpreting the world
Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Coding bonus: Bats’ hippocampal cells log spatial, social cues
The neurons represent not only an animal’s place in space, but also the distinguishing features of its fellow bats, including their sex and social status.
Coding bonus: Bats’ hippocampal cells log spatial, social cues
The neurons represent not only an animal’s place in space, but also the distinguishing features of its fellow bats, including their sex and social status.
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
Explore more from The Transmitter
On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.
On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.
NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.