Hippocampus

Recent articles

Two heatmap-like mouse silhouettes overlaid with a grid of ones and zeroes.

How artificial agents can help us understand social recognition

Neuroscience is chasing the complexity of social behavior, yet we have not answered the simplest question in the chain: How does a brain know “who is who”? Emerging multi-agent artificial intelligence may help accelerate our understanding of this fundamental computation.

By Eunji Kong
16 January 2026 | 5 min read

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch
Stack of papers.

What are the most-cited neuroscience papers from the past 30 years?

Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.

By The Transmitter
15 November 2025 | 11 min read
A man with glasses reads from a paper with a graph-like pattern of peaks and valleys on it.

The buzziest neuroscience papers of 2023, 2024

The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations, and more.

By Calli McMurray, Francisco J. Rivera Rosario
15 November 2025 | 18 min read
Colored outlines form the silhouette of a human brain in profile.

‘How to Change a Memory: One Neuroscientist’s Quest to Alter the Past,’ an excerpt

Part scientific exploration, part memoir, Steve Ramirez’s new book delves into the study of memory manipulation and his personal journey of discovery, friendship and grief.

By Steve Ramirez
7 November 2025 | 9 min read
Research image of portions of the adult dentate gyrus.

Machine learning spots neural progenitors in adult human brains

But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.

By Claudia López Lloreda
3 July 2025 | 6 min read
Research image of excitatory neurons in the mouse hippocampus.

Spatial learning circuitry fluctuates in step with estrous cycle in mice

Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

By Sydney Wyatt
25 June 2025 | 5 min read

Expanded view of hippocampal function comes into focus

After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.

By Natalia Mesa
24 June 2025 | 0 min watch
Photograph of a chickadee.

Gazing at a location from afar activates place cells in chickadees

The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

By Marta Hill
13 June 2025 | 6 min read
Illustration of synapse-like threads connecting in various ways.

Learning in living mice defies classic synaptic plasticity rule

Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

By Sydney Wyatt
28 May 2025 | 5 min read

Explore more from The Transmitter

After NINDS director ouster, 40 neuroscience organizations press U.S. Congress for oversight over hiring process

A letter signed by the groups asks Congress to ensure that scientific expertise remains a priority in the search for a new director of the National Institute of Neurological Disorders and Stroke.

By Angie Voyles Askham
23 January 2026 | 3 min read
Curvy lines link brain scans and a world map.

BRAIN Initiative researchers ‘dream big’ amid shifts in leadership, funding

But whether the initiative’s road map for the next decade is feasible remains an open question.

By Claudia López Lloreda
23 January 2026 | 6 min read
Two piggy banks whose slots form a plus symbol and a minus symbol.

Neuroscience, BRAIN Initiative gain budget in ‘bad’ NIH funding bill

The bill goes before the House of Representatives today and outlines increases for neuroscience-related research—including a 33 percent increase to the BRAIN Initiative—but maintains a multiyear spending approach that could limit the number of grants awarded overall.

By Angie Voyles Askham
22 January 2026 | 4 min read

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