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Portrait of Matthew Siegel sitting on a staircase.

Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel

A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.

By Katie Moisse
13 June 2024 | 7 min read
Illustration of a series of squares containing distinct patterns.

Can an emerging field called ‘neural systems understanding’ explain the brain?

This mashup of neuroscience, artificial intelligence and even linguistics and philosophy of mind aims to crack the deep question of what "understanding" is, however un-brain-like its models may be.

By George Musser
5 June 2024 | 21 min listen
Conceptual image of colorful falling letters, casting shadows on a white wall.

Some minimally verbal autistic people show signs of written-language familiarity, study suggests

But researchers not involved in the work worry the findings could be used to support discredited facilitated-communication techniques.

By Calli McMurray
9 May 2024 | 7 min read
Illustrated portrait of Emily Finn.
Synaptic Microphone

Brain connectivity and letting the data speak with Emily Finn

The Dartmouth College researcher talks about her quest to understand behavior and doing neuroscience “in the woods.”

By Brady Huggett
1 May 2024 | 69 min listen
Human head drawn in profile, brain area is red and connected to words spelled out in connected lines with nodes.

Individual neurons tune to complex speech sounds and cues

Neuropixels arrays implanted in people reveal nuances of speech perception and production that confirm results from brain-surface recordings and can even predict what someone is about to say.

By Elissa Welle
15 March 2024 | 7 min read
A research image of autism-linked genes.

Autism-linked perturbations converge on cell skeleton and RNA-binding proteins

The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.

By Giorgia Guglielmi
29 February 2024 | 4 min read

Controversial dyslexia study marred by methodological and ethical problems, researchers say

Subsequent studies have also failed to validate a range of products based on the work.

By Brendan Borrell
27 February 2024 | 8 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
An illustration of a hand placing letters spelling the word voice on a black board.
Spectrum Microphone

Debate unfurls over inclusivity and authenticity in research involving minimally verbal autistic people

Autism researchers can’t agree on how far to go to validate the input they gather from minimally verbal autistic people who use certain communication devices.

By Brendan Borrell
25 September 2023 | 11 min read
Five high-school-aged students sit on a bench looking at notebooks and a laptop.
Spectrum Microphone

Social skills decline during adolescence for a sliver of autistic youth

Most children with the condition, however, gain communication and social abilities over time.

By Calli McMurray
24 August 2023 | 4 min read

Explore more from The Transmitter

Illustration of children looking at a gigantic set of building blocks, some of which display genetic sequences on their surfaces.

Autism is more heritable in boys than in girls

If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.

Illustration of a brain.

This paper changed my life – ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read
Research image of microglia.

CDKL5 gene; cerebrospinal fluid; drug combo for fragile X syndrome

Here is a roundup of autism-related news and research spotted around the web for the week of 16 September.

By Jill Adams
17 September 2024 | 2 min read