Methylation

By Claudia López Lloreda

19 August 2026

5 min read

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

Organoids

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda

19 August 2026 | 5 min read

Fragile X syndrome

By Holly Barker

11 July 2023

6 min read

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

Fragile X syndrome

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

By Holly Barker

11 July 2023 | 6 min read

Genes

By Angie Voyles Askham

5 July 2023

5 min read

Illustration of a fragile X syndrome chromosome.

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

Genes

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

By Angie Voyles Askham

5 July 2023 | 5 min read