Methylation

Recent articles

Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

By Holly Barker
11 July 2023 | 6 min read
Illustration of a fragile X syndrome chromosome.

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

By Angie Voyles Askham
5 July 2023 | 5 min read

Explore more from The Transmitter

Nerve fibers from the human graft in mouse brain.

Human brain organoids flourish in emptied mouse cortex

The chimeric mice could help untangle the biology of human brain development or conditions such as autism.

By Brianna Abbott
16 September 2026 | 6 min read

What if Hegel were a neuroscientist?

Andrea Gambarotto shares what Hegel and enactivism have in common: an agency-first approach to understanding minds and brains.

By Paul Middlebrooks
16 September 2026 | 1 min read
Illustration of genetic associations.

This paper changed my life: Transformative work in addiction neuroscience

A 2011 Nature study found that loss of a nicotinic receptor subunit leads to increased nicotine intake in mice. The work set the standard for how to functionally validate genetic association study findings in neuroscience.

By Jibran Khokhar
16 September 2026 | 6 min read