Methylation

Recent articles

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

By Holly Barker
11 July 2023 | 6 min read
Illustration of a fragile X syndrome chromosome.

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

By Angie Voyles Askham
5 July 2023 | 5 min read

Explore more from The Transmitter

Head direction cells stably orient mice to outside world

The cells’ representations show little drift over time—unlike those of other navigation system neurons—and may provide a “rigid backbone” for more flexible sensory and cognitive responses.

By Angie Voyles Askham
25 March 2026 | 0 min watch

Juan Gallego discusses how manifolds are transforming our understanding of the coordination of neuronal population activity

A wealth of evidence supports the view that neural manifolds are real and useful, Gallego says, even if they may not completely solve the age-old mind-body problem.

By Paul Middlebrooks
25 March 2026 | 121 min listen
Research image of astrocytes in the mouse brain.

Astrocytes in mouse amygdala encode emotional state

The glial cells’ activity reliably tracks with freezing, hesitancy and other behaviors reminiscent of anxiety.

By Holly Barker
24 March 2026 | 4 min read