Neurodegenerative disorders
Recent articles
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”

Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Six new neuroscience books for fall—plus five titles you may have missed
We highlight the most anticipated neuroscience books for the remainder of 2024 and recap notable releases since last December.

Six new neuroscience books for fall—plus five titles you may have missed
We highlight the most anticipated neuroscience books for the remainder of 2024 and recap notable releases since last December.
Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.
Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.

Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.
Explore more from The Transmitter
‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux
Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.

‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux
Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.
‘Bioethics and Brains: A Disciplined and Principled Neuroethics,’ an excerpt
In their new book, published earlier this week, Giordano and Shook examine how ethics can guide neuroscience research and its real-world applications.

‘Bioethics and Brains: A Disciplined and Principled Neuroethics,’ an excerpt
In their new book, published earlier this week, Giordano and Shook examine how ethics can guide neuroscience research and its real-world applications.
AI tool estimates social ability by analyzing speech
The system’s code and training data—drawn from one of the largest databases of speech recordings from autistic people—are openly available.

AI tool estimates social ability by analyzing speech
The system’s code and training data—drawn from one of the largest databases of speech recordings from autistic people—are openly available.